My in-laws' computer is crawling with Trojans. Help!?

After their computer slowed to a crawl, they asked me to look at it. I installed a security suite which works great on my computer. It found 4 viruses, which could not be deleted, disinfected, or quarantined (apparently they're running in the background). I attempted to run the virus scan in Safe Mode, but the program wouldn't run. I know the names of at least two of the worms: Trojan-Downloader. Win32. Small. dkt and Trojan-Proxy. Win32. Lager.az. What are my options?

My in-laws' computer is crawling with Trojans. Help!?internet security software

I'm sure you paid alot of money for this security suite, but try using spybot search and destroy and or adaware (both free)

My in-laws' computer is crawling with Trojans. Help!?moto guzzi

here are some free programs to get ris of it. I like ewido the best.

Spybots search and Destroy http://www.download.com/3000-8022-101221...

adaware se%26gt; http://www.download.com/Ad-Aware-SE-Pers...

http://www.webroot.com/land/freescan.php

a-squared Free%26gt; http://www.emsisoft.com/en/software/free...

http://housecall.antivirus.com/housecall...

http://housecall65.trendmicro.com/

X -Cleaner Micro Edition scan http://www.spywareguide.com/onlinescan.p...